Andy Robinson has geared England up for an intense physical battle against Italy on Saturday, admitting: ''They will stand toe-to-toe with us.''
The Italians have failed to hold England on three previous occasions in Rome, conceding 154 points.
But they are hurting from last weekend's controversial RBS 6 Nations loss to Ireland in Dublin.
Refereeing decisions went against them against the Irish, and England boss Robinson expects Italy to come out firing at the Stadio Flaminio.
''We have always known that Italy have the physicality as a team, and apart from France, I think they are the most physical team we play against in the northern hemisphere,'' said Robinson.
''They will stand toe-to-toe with you, so up front will be a major physical battle for us.
''I think they have just added a bit of guile with the pace they are playing at, and I think their back-play has certainly improved and is pretty dangerous.
''What I saw last weekend was a side that were unfortunate to lose a game of rugby.
''If you think back last year to us in Dublin, then I think we were in a similar boat, feeling the same way. We were able to respond after that, and I think Italy will be looking to respond on Saturday.''
Robinson has made one enforced change from the team that demolished reigning Six Nations champions Wales at Twickenham last Saturday.
Full-back Josh Lewsey has not recovered from a shoulder injury sustained early in the game, and he is replaced by his Wasps colleague Tom Voyce, who makes a first Six Nations start.
Robinson, though, is optimistic that Lewsey will be fit in time for England's appointment with Scotland at Murrayfield on February 25.
Voyce took over from Lewsey during the 47-13 victory over Wales, and he rounded-off an impressive display by scoring England's sixth and final try.
With Voyce promoted to the starting line-up, there is a place on the bench for Gloucester's Teesside-born back James Simpson-Daniel.
Northampton wing Ben Cohen becomes the 21st England player to win 50 caps.
Simpson-Daniel apart, Robinson retains the bench which made such an impact during the Wales encounter, with Voyce and his fellow substitutes Lawrence Dallaglio and Matt Dawson scoring England's final three tries.
Dallaglio and Dawson can expect to be heavily involved on Saturday, and Robinson admits he was delighted with the impact his replacements made as Wales were put to the sword.
''I am not one for making a lot of substitutions, so it was something I had to look at myself,'' said Robinson.
''I believe we have a bench you want to put on and make those changes.
"I thought there was a huge impact from them and they really lifted the performance, but they lifted it based around an outstanding start to the game.
''On the back of that start, the guys were able to go on from the bench and really perform.''
England will find themselves two points clear at the championship summit if they beat Italy, France defeat Ireland then Wales recover from their Twickenham thrashing by seeing off Scotland in Cardiff on Sunday.
Six Nations history suggests England will have few problems reeling off a seventh successive triumph against Italy in the tournament, yet Robinson believes a tough task awaits.
''The squad understand we have to work hard to beat Italy,'' he said.
''It is about starting again. We have a different referee, we are playing against a different team, and we are not playing in the environment of Twickenham.
''Therefore, we have got to start the whole process again. It is not just going to happen, we have to work for each other, and that is the great thing about this team - the whole leadership and understanding of how we have to work to beat Italy.
''There is a tremendous energy among the players, and they want to play for each other, and we have to make sure we are streetwise in how we play the game.''
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