UP TO 400 jobs are to go at the GlaxoSmithKline plant at Barnard Castle over the next three years, it was announced yesterday afternoon.
Management said it was a direct result of the merger between Glaxo and SmithKline and the world-wide review of operations.
Mr John Teward, site director, said it was no reflection on the performance or commitment of the workforce.
"The Barnard Castle site will remain one of the largest in the GlaxoSmithKline global manufacturing network, employing approximately 1,100 people," he said.
"We will continue to play a key role, supplying important medicines to patients across the world."
He regretted the impact the proposal would have on the local community.
"However, as the major employer in Teesdale, we remain committed to the area and will continue to support economic development in the region," he said.
Talks with trade unions and staff representatives would begin and a full programme of support provided for those affected.
Coun John Watson, a former employee, said he was not surprised by the announcement, having read the statement of savings presented to shareholders following the merger.
"My only regret is that we had not made more provision for this eventuality," he said
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