Table-topping Wolviston, the only unbeaten side, start firm favourites against out-of-sorts Cleadon SC who have conceded 34 goals in six outings 2 including 17 in the last week.
Centre-back Simon Felstead is doubtful with a calf injury but midfielder Simon Colligan is fit and looks likely to return. Wolviston manager Graham Howard has strengthened the squad with the signing of striker Guy Whatmore from Thornaby.
It has been an horrendous start to the season for Cleadon, culminating in a 12-1 defeat last Saturday and a 5-0 reverse in midweek. Their problem has been an inability to field a strong side as Neil Heppel, Philip Shakespeare and Andrew Potts are playing cricket.
Lee Auty and Mark Johnson are suspended and to compound matters, Brian Tully is working.
Birtley Town suffered their first defeat on Wednesday but are still second just a point adrift of Wolviston. They face reigning champions North Shields and manager Dave Smith has several players carrying niggling injuries.
One definite absentee is goalkeeper Stephen Harrison with a knee injury.
North Shields hope Andy Elliott will return but the Robins have fitness doubts surrounding Eddie Miller, Stephen Routledge and Ian Dugdale.
Barnard Castle Glaxo are at home to Stokesley SC and have Paul Hedley and Nick Bellew returning, while Stokesley are boosted with the inclusion of Richard Hore, Richard Farrell and Paul Aldridge but goalkeeper Guy Ngansi and James Allen are still sidelined.
Annfield Plain meet Stanley United. The Plain will delay selection because of injury doubts.
Stanley United have Joncharles Gott, Chris Burn and Stephen Pigg unavailable but Neil Bewley is included.
Redcar Town are also struggling to cope with injuries and suspensions ahead of their home game with Ferryhill Athletic.
Boldon CA host New Marske with manager Norman Hunter delighted he has no injury worries.
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