The match of the day is at Ralph Gardner Park, where third-placed North Shields meet champions and current leaders Birtley Town.
Only three points separate the pair but the Robins have two games in hand on their rivals and a better goal difference.
"We have lost just once this season when Birtley beat us 2-1 so we have a score to settle," said North Shields secretary David Thompson, who reports that manager Wilf Keilty could start with the same team who played so well last weekend.
Striker Dominic Riley is added to the squad, while Birtley have no injury worries.
"We expect to be at full strength and after being held to a draw in our last game need to bounce back," said secretary Trevor Armstrong.
Stokesley SC, who are second, have been in tremendous form recently and victory in their home game over Barnard Castle Glaxo could take them into pole position.
Dean Talukder is supended but Ian Redpath and Michael Wilson both return. Barnard Castle are considerably stronger with the inclusion of Andrew Bellew, Simon Rathbone and Ross Murray.
New Marske visit Harton and Westoe and hope that Lee Lucas and Simon Welch will be able to play. The home side anticipate Scott Tooley will be available after being sidelined for a couple of months with a knee injury.
Robert Doyle is added to the squad but Shaun Frazer is still out with an injury to his shoulder.
Wolviston's home game with Whitehaven has been postponed.
It is all change for Boldon CA, who make the short journey to Cleadon SC.
Lee Seff and Andrew Whalley are banned and Ray Nesbitt injured but Michael Meek and Mark Harrison come back. Cleadon miss Lee Auty as they attempt to close in on the top three.
Darlington RA meet Gateshead Reserves at the International Stadium minus Mark Brookes, who will miss the remainder of the season because of a problem with his shoulder.
Dave Alderson is added to Dave Woodcock's pool of players while Gateshead boss Alan Bell reports that youngster John Lognonne could make his debut in goal.
Washington Nissan UK miss suspended pair Steve Smith and Paul Smith at Annfield Plain and for their journey to Windscale, Ryhope CW cannot call upon George Marley or David Crosby.
They also have injury doubts surrounding Liam Routledge, Paul Hamilton and Kevin Berry but keeper Michael Burlinson and John Bell are free to play.
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