Billingham Synthonia scored one of the fastest FA Cup goals of the season when they scored after just 22 seconds to set up a 5-0 win at Brandon on Saturday.
Brandon had a man sent off last Saturday in the first minute when the two sides met in the league, and this time they conceded a goal when Micky Dunwell broke clear and fired home.
Lee Flanagan set up Colin Iley to score the second with a header, and just before half-time Iley sidefooted the third.
Synners also scored a quick goal after fifty seconds at the start of the second half through Dunwell, and after 70 minutes Dunwell completed his hat trick from a Neil Radigan corner.
Brandon boss Alan Shoulder, who was forced to play the full ninety minutes for his side because of injuries, said: "We knew it was going to be difficult before the game, but it was uphill after they scored in the first minute."
West Auckland will play at Whickham next Sunday after they beat neighbours Shildon, who had midfielder Brian Smith dismissed for swearing after 20 minutes.
West took the lead when Mattie Moffat scored from a loose ball, but Shildon hit back and levelled with a free-kick by Michael Hillary.
But West got the winner when Danny Key set up Moffat to run through and chip the keeper.
Esh Winning and Ashington shared eight goals and must replay on Tuesday night.
Esh were behind three times in the game. Alan Hogg headed Ashington into the lead, but Esh levelled through Kevin Hamilton from the penalty spot after Craig Coates was fouled. Alex Lawson scored from a rebound to put Ashington 2-1 up, only for Ben Wicling to equalise with a 30 yarder.
Andrew Soppitt put Esh into the lead for the only time on 50 minutes, only for Ashington to level again through Alan Hogg. Ross Atkinson put Ashington 4-3 up with an overhead kick, but Esh earned a replay with a Craig Coates effort.
Bedlington won their local derby 4-2 at Newcastle Benfield. Michael Robinson put Bedlington into the lead on four minutes, but Benfield levelled when Micky Chilton scored from a Dean Fuller cross.
Steve Preen set up Tony Shandran to put Bedlington back into the lead in the first minute of the second half, but Chilton scored his second from a long ball. Shandran, however, put Bedlington back into the lead from a left wing cross, and he completed his hat-trick in the last minute.
Tow Law gained a morale boosting win when they beat Squires Gate 2-0 at Ironworks Road. Stuart Niven scored early on for Tow Law, then Nicky Martin made a place in the next round safe in the second half.
Consett must replay on Wednesday night after they drew 1-1 at Formby thanks to a last minute goal from Gary Forbes.
Horden came from behind to win 3-1 at Prudhoe. The home side took the lead through a goal by Mark Drysdale, but Lee Ure equalised with a shot into the top corner of the net. Martin O'Riordan put Horden in front from the spot following a foul, and in the second half George Woodhouse made it 3-1.
Newcastle Blue Star won 2-1 at Blackpool Mechanics. Christian Graham and George Woodhouse scored for the Star after 23 and 38 minutes.
Hebburn also had a good win, by 2-1 at Flixton, scoring both their goals in the first twenty minutes through Owen Peterson and Garry McCartney.
Guisborough face a replay tonight with Great Harwood after they drew 1-1 at the King George, Carl Tate scoring for Guisborough.
North Shields went down 1-0 at Winterton.
In the other ties, Jarrow Roofing lost 4-0 at home to Sheffield, West Allotment were beaten 4-1 at Cammell Laird, and Morpeth went down 1-0 at Oldham Town.
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